Clinical Pharmacologist

Shape clinically plausible pharmacology datasets and supporting scientific content for multiple workflows, with responsibility for ensuring pharmacokinetic and pharmacodynamic outputs align with efficacy and safety results.

• Simulate the clinical pharmacology layer of each data room, including PK and PD datasets, dosing and escalation regimens, exposure-response relationships, and bioanalytical reports.
• Ensure dose rationale and concentration data are clinically plausible and reconcile with efficacy and safety outputs.
• Author dose-selection rationale, drug concentration and response sections, and content addressing drug-drug and drug-disease interactions.
• Design prompts, reference outputs, and evaluation rubrics to measure an AI agent''s ability to complete comparable clinical pharmacology work.

• PharmD, MD, PhD in pharmacology, pharmacokinetics, or a related field, or equivalent.
• At least 5 years of experience required; 10 to 25 years preferred.
• Experience supporting pre-market Phase 1, 2, or 3 programs as a clinical pharmacologist.
• Hands-on expertise in PK/PD, dose selection and escalation, and exposure-response analysis.
• First-in-human program experience is strongly preferred.
• Ability to work from a protocol and statistical analysis plan to produce pharmacology data that withstands expert review.

• Remote, hourly engagement.
• Minimum availability of 20 to 25 hours per week; 30 or more hours per week preferred.

$120 to $170 per hour.

Applicants must be located in the United States, Canada, or France.